DTX4 Rabbit Polyclonal Antibody
Frequently bought together (2)
Transient overexpression lysate of deltex homolog 4 (Drosophila) (DTX4)
USD 605.00
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Specifications
Product Data | |
Applications | WB |
Recommended Dilution | WB: 1 - 2 ug/mL |
Reactivities | Human, Mouse, Rat |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | PACS2 antibody was raised against a 17 amino acid peptide near the center of human PACS2. |
Formulation | PBS containing 0.02% sodium azide. |
Concentration | 1 mg/ml |
Purification | PACS2 antibody is affinity chromatography purified via peptide column. |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | Predicted: 98 kDa; Observed: 95 kDa |
Gene Name | deltex 4, E3 ubiquitin ligase |
Database Link | |
Background | PACS2 (phosphofurin acidic cluster sorting protein-2), PACS1L, is an 889 amino acid protein that localizes to both the mitochondrion and the lumen of the endoplasmic reticulum (ER) and belongs to the PACS family (1,2). It is expressed in a broad range of tissues with highest expression in skeletal muscle, brain, heart, testis and pancreas (2,). PACS2 interacts with Polycystin-2 and BID and functions as a sorting protein that regulates mitochondria-ER communication and is thought to be involved in ion channel trafficking, specifically direct cluster-containing ion channels to distinct subcellular compartments (3-5). |
Synonyms | RNF155 |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | Notch signaling pathway |
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Product Manuals |
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