VTI1A Rabbit Polyclonal Antibody

CAT#: TA349197

Rabbit Polyclonal Anti-VTI1a Antibody

Product Images

Western blot analysis of VTI1a in human brain tissue lysate with VTI1a antibody at 1 ug/mL.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1 - 2 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: VTI1a antibody was raised against a 19 amino acid peptide near the center of human VTI1a.
• Formulation: PBS containing 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: VTI1a antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: Predicted: 24, 27 kDa; Observed: 26 kDa
• Gene Name: vesicle transport through interaction with t-SNAREs 1A
• Database Link:
  NP_660207
  Entrez Gene 53611 MouseEntrez Gene 65277 RatEntrez Gene 143187 Human
  UniProt ID Q96AJ9
• Background: Vesicle transport through interaction with t-SNAREs homolog 1 (VTI1a and VTI1b) are involved in vesicular transport from the late endosomes to the trans-Golgi network (1). They are both localized in the trans-Golgi network, with VTI1a also found in the Golgi apparatus and VTI1b in endosomes (2,3). VTI1a mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane and promotes fusion of the lipid bilayers (4). VTI1a may be concerned with increased secretion of cytokines associated with cellular senescence (5).
• Synonyms: MMDS3; MVti1; Vti1-rp2; VTI1RP2

Reference Data

• Protein Families: Transmembrane
• Protein Pathways: SNARE interactions in vesicular transport