PRPS1 Rabbit Polyclonal Antibody

CAT#: TA349256

Rabbit Polyclonal Anti-BACE1 Antibody

Product Images

Gel: 8%SDS-PAGE, Lysate: 100 ug, Lane: Human fetal brain tissue, Primary antibody: (BACE1 Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 2000-5000, WB: 500-2000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human BACE1
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 56 kDa
• Gene Name: phosphoribosyl pyrophosphate synthetase 1
• Database Link:
  NP_002755
  Entrez Gene 5631 Human
  UniProt ID P60891
• Background: Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is the protein encoded by this gene. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. Multiple transcript variants encoding different isoforms have been described for this gene.
• Synonyms: ARTS; CMTX5; DFN2; DFNX1; PPRibP; PRS-I; PRSI

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Metabolic pathways, Pentose phosphate pathway, Purine metabolism