Histone H3.3C (H3F3C) Rabbit Polyclonal Antibody

CAT#: TA349339

Rabbit Polyclonal Anti-H3F3C Antibody

Product Images

Gel: 12%SDS-PAGE Lysate: 20 μg Lane 1-2: Human fetal brain tissue Hela cells Primary antibody: TA349339 (H3-5 Antibody) at dilution 1/250 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 10 seconds

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 200-1000
  WB positive control: Human fetal brain tissue and Hela cells
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human H3F3C
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 15 kDa
• Gene Name: H3 histone, family 3C
• Database Link:
  NP_001013721
  Entrez Gene 440093 Human
  UniProt ID Q6NXT2
• Background: Eukaryotic histones are basic and water soluble nuclear proteins that form hetero-octameric nucleosome particles by wrapping 146 base pairs of DNA in a left-handed super-helical turn sequentially to form chromosomal fiber. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form the octamer; formed of two H2A-H2B dimers and two H3-H4 dimers, forming two nearly symmetrical halves by tertiary structure. Over 80% of nucleosomes contain the linker Histone H1, derived from an intronless gene, that interacts with linker DNA between nucleosomes and mediates compaction into higher order chromatin.
• Synonyms: H3.5

Reference Data

• Protein Pathways: Systemic lupus erythematosus