HDAC8 Rabbit Polyclonal Antibody

CAT#: TA349342

Rabbit Polyclonal Anti-HDAC8 Antibody

Product Images

Gel: 8%SDS-PAGE Lysate: 40 μg Lane: 293T cells Primary antibody: TA349342 (HDAC8 Antibody) at dilution 1/950 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 3 seconds

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  Immunohistochemistry of paraffin-embedded Human tonsil tissue using TA349342 (HDAC8 Antibody) at dilution 1/40 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human tonsil tissue using TA349342 (HDAC8 Antibody) at dilution 1/40, treated with fusion protein. (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using TA349342 (HDAC8 Antibody) at dilution 1/40 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using TA349342 (HDAC8 Antibody) at dilution 1/40, treated with fusion protein. (Original magnification: ×200)

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Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: 293T cells
  IHC: 50-200
  Positive control: Human tonsil
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human HDAC8
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 42 kDa
• Gene Name: histone deacetylase 8
• Database Link:
  NP_060956
  Entrez Gene 70315 MouseEntrez Gene 363481 RatEntrez Gene 55869 Human
  UniProt ID Q9BY41
• Background: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors.
• Synonyms: CDA07; CDLS5; HD8; HDACL1; MRXS6; RPD3; WTS

Reference Data

• Protein Families: Druggable Genome, Transcription Factors