ARHGEF1 Rabbit Polyclonal Antibody

CAT#: TA349509

Rabbit Polyclonal Anti-ARHGEF1 Antibody

Specifications

Product Data

• Applications: ELISA, IHC
• Recommended Dilution: IHC: 50-200
  Positive control: Human thyroid cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human ARHGEF1
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: Rho guanine nucleotide exchange factor 1
• Database Link:
  NP_945328
  Entrez Gene 16801 MouseEntrez Gene 60323 RatEntrez Gene 9138 Human
  UniProt ID Q92888
• Background: Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate Rho-dependent signals. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined.
• Synonyms: GEF1; LBCL2; LSC; P115-RHOGEF; SUB1.5

Reference Data

• Protein Pathways: Regulation of actin cytoskeleton, Vascular smooth muscle contraction