p90 Autoantigen (KIAA1524) Rabbit Polyclonal Antibody

CAT#: TA349807

Rabbit Polyclonal Anti-KIAA1524 Antibody

Product Images

Gel: 6%SDS-PAGE Lysate: 40 μg Lane 1-2: A431 cells lovo cells Primary antibody: TA349807 (CIP2A Antibody) at dilution 1/597 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 1 second

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 500-2000
  WB positive control: A431 and lovo cells
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human KIAA1524
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 102 kDa
• Gene Name: KIAA1524
• Database Link:
  NP_065941
  Entrez Gene 57650 Human
  UniProt ID Q8TCG1
• Background: Protein CIP2A also known as cancerous inhibitor of PP2A (CIP2A) is a protein that in humans is encoded by the KIAA1524 gene. Protein phosphatase 2A (PP2A) is a cellular tumor suppressor which inhibits cell proliferation and transformation of normal cells to malignant cancer cells. Inhibition of PP2A activity is a prerequisite for human cell transformation. However, the in vivo mechanisms by which PP2A activity is inhibited in spontaneously transformed human cancer cells have been unclear.
• Synonyms: CIP2A; p90

Reference Data

• Protein Families: Druggable Genome