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DR6 (TNFRSF21) Rabbit Polyclonal Antibody
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Other products for "TNFRSF21"
Specifications
| Product Data | |
| Applications | IHC |
| Recommended Dilution | IHC: 25-100 Positive control: Human thyroid cancer Predicted cell location: Cytoplasm |
| Reactivities | Human, Mouse, Rat |
| Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human TNFRSF21 |
| Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glyceroln |
| Concentration | lot specific |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Gene Name | tumor necrosis factor receptor superfamily member 21 |
| Database Link | |
| Background | This gene encodes a member of the tumor necrosis factor receptor superfamily. The encoded protein activates nuclear factor kappa-B and mitogen-activated protein kinase 8 (also called c-Jun N-terminal kinase 1), and induces cell apoptosis. Through its death domain, the encoded receptor interacts with tumor necrosis factor receptor type 1-associated death domain (TRADD) protein, which is known to mediate signal transduction of tumor necrosis factor receptors. |
| Synonyms | BM-018; CD358; DR6 |
| Reference Data | |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Cytokine-cytokine receptor interaction |
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