ECE2 (EEF1AKMT4) Rabbit Polyclonal Antibody

CAT#: TA349914

Rabbit Polyclonal Anti-ECE2 Antibody

Product Images

Gel: 6%SDS-PAGE Lysate: 40 μg Lane 1-2: A172 cells Mouse liver tissue Primary antibody: TA349914 (EEF1AKMT4 Antibody) at dilution 1/350 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 20 seconds

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  Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using TA349914 (EEF1AKMT4 Antibody) at dilution 1/25 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using TA349914 (EEF1AKMT4 Antibody) at dilution 1/25, treated with fusion protein. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: A172 cells and Mouse liver tissue
  IHC: 30-150
  Positive control: Human ovarian cancer
  Predicted cell location: Cytoplasm and Nucleus
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human ECE2
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 100 kDa
• Gene Name: endothelin converting enzyme 2
• Database Link:
  NP_115707
  Entrez Gene 110599564 Entrez Gene 9718 Human
• Background: This gene encodes a member of the M13 family, which includes type 2 integral membrane metallopeptidases. The encoded enzyme is a membrane-bound zinc-dependent metalloprotease. The enzyme catalyzes the cleavage of big endothelin to produce the vasoconstrictor endothelin-1, and plays a role in the processing of several neuroendocrine peptides. It may also have methyltransferase activity. Alternative splicing results in multiple transcript variants.
• Synonyms: KIAA0604; MGC2408; MGC17664; MGC78487