RAIDD (CRADD) Rabbit Polyclonal Antibody

CAT#: TA350324

Rabbit Polyclonal Anti-CRADD Antibody

Product Images

Immunohistochemistry of paraffin-embedded Human lung cancer tissue using TA350324 (CRADD Antibody) at dilution 1/25 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human lung cancer tissue using TA350324 (CRADD Antibody) at dilution 1/25, treated with fusion protein. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 25-100
  Positive control: Human lung cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human CRADD
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: CASP2 and RIPK1 domain containing adaptor with death domain
• Database Link:
  NP_003796
  Entrez Gene 8738 Human
  UniProt ID P78560
• Background: The protein encoded by this gene is a death domain (CARD/DD)-containing protein and has been shown to induce cell apoptosis. Through its CARD domain, this protein interacts with, and thus recruits, caspase 2/ICH1 to the cell death signal transduction complex that includes tumor necrosis factor receptor 1 (TNFR1A), RIPK1/RIP kinase, and numbers of other CARD domain-containing proteins.
• Synonyms: MRT34; RAIDD

Reference Data

• Protein Families: Druggable Genome