Unrip (STRAP) Rabbit Polyclonal Antibody

CAT#: TA350582

Rabbit Polyclonal Anti-STRAP Antibody

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: 293T, Jurkat, RAW264.7, Hela cell, Mouse brain tissue lysates
  IHC: 50-200
  Positive control: Human cervical cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Full length fusion protein
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 38 kDa
• Gene Name: serine/threonine kinase receptor associated protein
• Database Link:
  NP_009109
  Entrez Gene 20901 MouseEntrez Gene 297699 RatEntrez Gene 11171 Human
  UniProt ID Q9Y3F4
• Background: Serine-threonine kinase receptor-associated protein is an enzyme that in humans is encoded by the STRAPgene. The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP.
• Synonyms: MAWD; PT-WD; UNRIP

Reference Data

• Protein Families: Druggable Genome