WNK3 Rabbit Polyclonal Antibody

CAT#: TA350767

Rabbit Polyclonal Anti-WNK3 Antibody

Product Images

Gel: 6%SDS-PAGE, Lysate: 40 ug, Lane: Hela cells, Primary antibody: (WNK3 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 minutes

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  The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using (WNK3 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: ELISA: 1000-2000, WB: 200-1000, IHC: 25-100
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human WNK3
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 198 kDa
• Gene Name: WNK lysine deficient protein kinase 3
• Database Link:
  NP_065973
  Entrez Gene 279561 MouseEntrez Gene 65267 Human
  UniProt ID Q9BYP7
• Background: This gene encodes a protein belonging to the 'with no lysine' family of serine-threonine protein kinases. These family members lack the catalytic lysine in subdomain II, and instead have a conserved lysine in subdomain I. This family member functions as a positive regulator of the transcellular Ca2+ transport pathway, and it plays a role in the increase of cell survival in a caspase-3-dependent pathway. Alternative splicing results in multiple transcript variants.
• Synonyms: PRKWNK3

Reference Data

• Protein Families: Druggable Genome, Protein Kinase