KMT2D Rabbit Polyclonal Antibody

CAT#: TA350782

Rabbit Polyclonal Anti-KMT2D Antibody

Product Images

Immunohistochemistry of paraffin-embedded Human brain tissue using TA350782 (KMT2D Antibody) at dilution 1/40 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human brain tissue using TA350782 (KMT2D Antibody) at dilution 1/40, treated with synthetic peptide. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 50-200
  Positive control: Human brain
  Predicted cell location: Nucleus
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human KMT2D
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: lysine methyltransferase 2D
• Database Link:
  NP_003473
  Entrez Gene 8085 Human
  UniProt ID O14686
• Background: The protein encoded by this gene is a histone methyltransferase that methylates the Lys-4 position of histone H3. The encoded protein is part of a large protein complex called ASCOM, which has been shown to be a transcriptional regulator of the beta-globin and estrogen receptor genes. Mutations in this gene have been shown to be a cause of Kabuki syndrome.
• Synonyms: AAD10; ALR; CAGL114; KABUK1; KMS; MLL2; MLL4; TNRC21

Reference Data

• Protein Families: Druggable Genome