Synapsin I (SYN1) Rabbit Polyclonal Antibody

CAT#: TA350839

Rabbit Polyclonal Anti-SYN1 Antibody

Product Images

Gel: 8%SDS-PAGE Lysate: 30 μg Lane: Mouse brain tissue Primary antibody: TA350839 (SYN1 Antibody) at dilution 1/900 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 2 seconds

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 500-2000
  WB positive control: Mouse brain tissue
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human SYN1
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 74 kDa
• Gene Name: synapsin I
• Database Link:
  NP_598006
  Entrez Gene 20964 MouseEntrez Gene 24949 RatEntrez Gene 6853 Human
  UniProt ID P17600
• Background: This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family plays a role in regulation of axonogenesis and synaptogenesis. The protein encoded serves as a substrate for several different protein kinases and phosphorylation may function in the regulation of this protein in the nerve terminal. Mutations in this gene may be associated with X-linked disorders with primary neuronal degeneration such as Rett syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified
• Synonyms: SYN1a; SYN1b; SYNI