Centaurin gamma 1 (AGAP2) Rabbit Polyclonal Antibody

CAT#: TA351073

Rabbit Polyclonal Anti-AGAP2 Antibody

Product Images

Gel: 6%SDS-PAGE, Lysate: 40 ug, Lane: Hela cells, Primary antibody: (AGAP2 Antibody) at dilution 1/700, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 40 seconds

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  The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using (AGAP2 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200)

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  The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using (AGAP2 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: ELISA: 2000-5000, WB: 500-2000, IHC: 50-200
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human AGAP2
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 125 kDa
• Gene Name: ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
• Database Link:
  NP_001116244
  Entrez Gene 116986 Human
  UniProt ID Q99490
• Background: The protein encoded by this gene belongs to the centaurin gamma-like family. It mediates anti-apoptotic effects of nerve growth factor by activating nuclear phosphoinositide 3-kinase. It is overexpressed in cancer cells, and promotes cancer cell invasion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
• Synonyms: CENTG1; GGAP2; PIKE

Reference Data

• Protein Pathways: Endocytosis