Mannose Receptor (MRC1) Rabbit Polyclonal Antibody

CAT#: TA351084

Rabbit Polyclonal Anti-MRC1 Antibody

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 15-50
  Positive control: Human liver cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human MRC1
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: mannose receptor, C type 1
• Database Link:
  NP_002429
  Entrez Gene 4360 Human
  UniProt ID P22897
• Background: The recognition of complex carbohydrate structures on glycoproteins is an important part of several biological processes, including cell-cell recognition, serum glycoprotein turnover, and neutralization of pathogens. The protein encoded by this gene is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. The protein has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment.
• Synonyms: bA541I19.1; CD206; CLEC13D; CLEC13DL; MMR; MRC1L1

Reference Data

• Protein Families: Druggable Genome, Transmembrane