DBC2 (RHOBTB2) Rabbit Polyclonal Antibody

CAT#: TA351125

Rabbit Polyclonal Anti-RHOBTB2 Antibody

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 25-100
  Positive control: Human thyroid cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human RHOBTB2
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: Rho related BTB domain containing 2
• Database Link:
  NP_055993
  Entrez Gene 246710 MouseEntrez Gene 23221 Human
  UniProt ID Q9BYZ6
• Background: The protein encoded by this gene is a small Rho GTPase and a candidate tumor suppressor. The encoded protein interacts with the cullin-3 protein, a ubiquitin E3 ligase necessary for mitotic cell division. This protein inhibits the growth and spread of some types of breast cancer. Three transcript variants encoding different isoforms have been found for this gene.
• Synonyms: DBC2

Reference Data

• Protein Pathways: Ubiquitin mediated proteolysis