Plexin D1 (PLXND1) Rabbit Polyclonal Antibody

CAT#: TA351543

Rabbit Polyclonal Anti-PLXND1 Antibody

Product Images

Gel: 6%SDS-PAGE Lysate: 40 μg Lane: Hbmec cells Primary antibody: TA351543 (PLXND1 Antibody) at dilution 1/200 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 10 minutes

• 

  Immunohistochemistry of paraffin-embedded Human prostate cancer tissue using TA351543 (PLXND1 Antibody) at dilution 1/40 (Original magnification: ×200)

• 

  Immunohistochemistry of paraffin-embedded Human prostate cancer tissue using TA351543 (PLXND1 Antibody) at dilution 1/40, treated with synthetic peptide. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: IHC: 20-100
  Positive control: Human liver cancer
  Predicted cell location: Cytoplasm or Nucleus
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human PLXND1
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 212 kDa
• Gene Name: plexin D1
• Database Link:
  NP_055918
  Entrez Gene 67784 MouseEntrez Gene 312652 RatEntrez Gene 23129 Human
  UniProt ID Q9Y4D7
• Background: Cell surface receptor for SEMA4A and for class 3 semaphorins, such as SEMA3A, SEMA3C and SEMA3E. Plays an important role in cell-cell signaling, and in regulating the migration of a wide spectrum of cell types. Regulates the migration of thymocytes in the medulla. Regulates endothelial cell migration. Plays an important role in ensuring the specificity of synapse formation. Required for normal development of the heart and vasculature By similarity. Mediates anti-angiogenic signaling in response to SEMA3E.
• Synonyms: PLEXD1

Reference Data

• Protein Families: Druggable Genome, Transmembrane