RNF43 Rabbit Polyclonal Antibody

CAT#: TA351607

Rabbit Polyclonal Anti-RNF43 Antibody

Product Images

Gel: 6%SDS-PAGE Lysate: 40 μg Lane: Jurkat cells Primary antibody: TA351607 (RNF43 Antibody) at dilution 1/300 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 30 seconds

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 200-1000
  WB positive control: Human fetal brain tissue
  IHC: 25-100
  Positive control: Human liver cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human RNF43
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 86 kDa
• Gene Name: ring finger protein 43
• Database Link:
  NP_060233
  Entrez Gene 54894 Human
  UniProt ID Q68DV7
• Background: RNF43 (ring finger protein 43), also known as URCC or RNF124, is a 783 amino acid single-pass type I membrane protein of the Endoplasmic reticulum and nuclear envelope that is thought to function as an E3 ubiquitin-protein ligase. Containing one RING-type zinc finger and existing as four alternatively spliced isoforms, RNF43 is expressed in fetal kidney and lung, as well as in cancers of the lung, colon and kidney. RNF43 functions as a cytotoxic T lymphocyte tumor antigen, and is therefore considered a target for cancer immunotherapy.
• Synonyms: RNF124; SSPCS; URCC

Reference Data

• Protein Families: Druggable Genome, Secreted Protein, Transmembrane