SENP6 Rabbit Polyclonal Antibody

CAT#: TA351650

Rabbit Polyclonal Anti-SENP6 Antibody

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 200-1000
  WB positive control: Hela and K562 cells
  IHC: 25-100
  Positive control: Human breast cancer
  Predicted cell location: Nucleus
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human SENP6
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 126 kDa
• Gene Name: SUMO1/sentrin specific peptidase 6
• Database Link:
  NP_056386
  Entrez Gene 26054 Human
  UniProt ID Q9GZR1
• Background: Ubiquitin-like molecules (UBLs), such as SUMO1 (UBL1; MIM 601912), are structurally related to ubiquitin (MIM 191339) and can be ligated to target proteins in a similar manner as ubiquitin. However, covalent attachment of UBLs does not result in degradation of the modified proteins. SUMO1 modification is implicated in the targeting of RANGAP1 (MIM 602362) to the nuclear pore complex, as well as in stabilization of I-kappa-B-alpha (NFKBIA; MIM 164008) from degradation by the 26S proteasome.
• Synonyms: SSP1; SUSP1

Reference Data

• Protein Families: Druggable Genome, Protease