Siglec 7 (SIGLEC7) Rabbit Polyclonal Antibody
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Specifications
Product Data | |
Applications | IHC |
Recommended Dilution | IHC: 25-100 Positive control: Human prostate cancer Predicted cell location: Cytoplasm or Cell membrane |
Reactivities | Human |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Synthetic peptide of human SIGLEC7 |
Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glyceroln |
Concentration | lot specific |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Gene Name | sialic acid binding Ig like lectin 7 |
Database Link | |
Background | Siglec-7, which is highly expressed in monocytes and resident blood cells but not in parenchymatous cells, mediates inhibition of natural killer cell cytotoxicity. Due to alternative splicing events, two isoforms exist for Siglec-12, namely SLG-L (the long isoform) and SLG-S (the shorter isoform). These isoforms are differentially expressed with the longer isoform predominantly found in small intestine, spleen and bone marrow, and the shorter isoform predominantly found in small intestine, spleen and adrenal gland. |
Synonyms | AIRM1; CD328; CDw328; D-siglec; p75; QA79; SIGLEC-7; SIGLEC19P; SIGLECP2 |
Reference Data | |
Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Transmembrane |
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