CLDND2 Rabbit Polyclonal Antibody

CAT#: TA352008

Rabbit Polyclonal Anti-CLDND2 Antibody

Product Images

Gel: 12%SDS-PAGE Lysate: 40 μg Lane 1-4: Hela 293T PC3 and TM4 cell Primary antibody: TA352008 (CLDND2 Antibody) at dilution 1/400 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 30 seconds

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  Immunohistochemistry of paraffin-embedded Human breast cancer tissue using TA352008 (CLDND2 Antibody) at dilution 1/45 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human breast cancer tissue using TA352008 (CLDND2 Antibody) at dilution 1/45, treated with synthetic peptide. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 200-1000
  WB positive control: Human colon sigmoideum cancer tissue
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human CLDND2
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: claudin domain containing 2
• Database Link:
  NP_689566
  Entrez Gene 125875 Human
  UniProt ID Q8NHS1
• Background: CLDND2 (claudin domain containing 2) is a 167 amino acid multi-pass membrane protein that belongs to the PMP-22/EMP/MP20 family and is encoded by a gene that maps to human chromosome 19q13.33. Consisting of around 63 million bases with over 1,400 genes, chromosome 19 makes up over 2% of human genomic DNA. Chromosome 19 includes a diversity of interesting genes and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin superfamily members including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family, and Fc receptors. Key genes for eye color and hair color also map to chromosome 19. Peutz-Jeghers syndrome, spinocerebellar ataxia type 6, the stroke disorder CADASIL, hypercholesterolemia and insulin-dependent diabetes have been linked to chromosome 19.
• Synonyms: MGC33839

Reference Data

• Protein Families: Transmembrane