ADAM19 Rabbit Polyclonal Antibody

CAT#: TA352953L

Rabbit polyclonal anti-ADAM19 antibody

Product Images

Western blot analysis of mouse primary osteoblasts probed with whole ADAM19 antiserum at a 1:500 dilution.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: ADAM19
• Concentration: lot specific
• Purification: Unpurified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: ~120 kDa
• Gene Name: ADAM metallopeptidase domain 19
• Database Link:
  NP_150377
  Entrez Gene 11492 MouseEntrez Gene 8728 Human
  UniProt ID Q9H013
• Background: ADAM19, is a member of the ADAM (a disintegrin and metalloprotease-like domain) family. It has been cloned from mouse and human. ADAM19 was first described in muscle cells as a protein with homology to the fertilins (ADAMs 1 and 2). Initial observations indicated a role for ADAM19 in myoblast fusion, similar to sperm-egg fusion aided by ADAMs 1 and 2. Later works describe ADAM19 in the bone, muscle, lung, heart, brain, kidney, and a wide range of tissues. Also reported is a sequence of ADAM19 lacking the transmembrane and cytoplasmic domains, suggesting that a soluble form is produced. Other ADAMs family members (ADAM-10, ADAM-17) have been more thoroughly studied, and are known to play key roles in inflammation, growth factor maturation and release, and a wide range of other functions.
• Synonyms: FKSG34; MADDAM; MLTNB
• Note: Suggested dilution for western blot: 1:500

Reference Data

• Protein Families: Druggable Genome, Transmembrane