CD8A Mouse Monoclonal Antibody [Clone ID: Bu88]

CAT#: TA353073L

Mouse monoclonal Anti-Leu2 Clone BU88

Specifications

Product Data

• Clone Name: Bu88
• Recommended Dilution: FACS ; IHC
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: CD8 enriched peripheral blood lymphocytes
• Formulation: PBS with 0.02% Sodium Azide
• Concentration: lot specific
• Purification: Purified by affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: CD8a molecule
• Database Link:
  NP_741969
  Entrez Gene 925 Human
  UniProt ID P01732
• Background: Leu-2 is a T cell co-receptor that recognises, together with the T cell receptor, MHC class I molecules. Leu-2 is present on human suppressor / cytotoxic T cells, 30% of circulating T cells. BU88 may be used for the detection of immunoregulatory T cell subset imbalance in autoimmune and immunodeficiency states, categorisation of T cell acute lymphoblastic leukaemia and lymphoblastic lymphoma and T4/T8 ratios in rheumatoid arthritis, multiple sclerosis, etc.
• Synonyms: CD8; Leu2; MAL; p32
• Note: BU88 binds 3 out of 4 types of T Cell.

Reference Data

• Protein Families: Adult stem cells, Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein, Transmembrane
• Protein Pathways: Antigen processing and presentation, Cell adhesion molecules (CAMs), Hematopoietic cell lineage, Primary immunodeficiency, T cell receptor signaling pathway