Clec1b Rat Monoclonal Antibody [Clone ID: 17D9]

CAT#: TA353098L

Rat monoclonal Anti-CLEC2 Clone 17D9

Product Images

Usage of 17D9 for inducing CLEC-2 signalling: Lysates of BMDC stimulated with 17D9 or isotype matched mAb of irrelevant specificity were analysed by western blot using anti-phospho-Syk and anti-Syk antibodies

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  Specificity of anti-mouse CLEC-2 monoclonal antibody 17D9 for FACS.

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  Usage of 17D9 for inducing CLEC-2 signalling: LK cells ectopically expressing wild-type mouse CLEC-2 (WT) or the intracellular tyrosine mutant (Y7F) were stimulated with17D9

Specifications

Product Data

• Clone Name: 17D9
• Applications: Assay, FC, WB
• Recommended Dilution: FACS ; WB
• Reactivities: Mouse
• Host: Rat
• Isotype: IgG2b
• Clonality: Monoclonal
• Immunogen: RBL-2H3 cells stably expressing HA-tagged mouse CLEC-2
• Formulation: PBS with 0.02% Sodium Azide
• Concentration: lot specific
• Purification: Purified by affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: C-type lectin domain family 1, member b
• Database Link:
  NP_064369
  Entrez Gene 56760 Mouse
  UniProt ID Q9JL99
• Background: CLEC-2 belongs to a sub-family of C-type lectin receptors that signal through Syk via a single YxxL motif (hemITAM). This antibody can be used as a selective agonist of CLEC-2 and also to study its expression pattern.
• Synonyms: 1810061I13Rik; CLEC-2; CLEC2; CLEC2B; PRO1384; QDED721
• Note: Recommended Concentrations: 10ug/ml for FACS, 50ug/ml for agonistic activity, 2ug/ml for Western.