Factor VII (F7) Mouse Monoclonal Antibody [Clone ID: RFF-VII/2]

CAT#: TA353175L

Mouse monoclonal Anti-Factor VII Clone RFF-VII/2

Specifications

Product Data

• Clone Name: RFF-VII/2
• Recommended Dilution: ELISA ; Functional ; WB
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1, kappa
• Clonality: Monoclonal
• Immunogen: Purified human Factor VII
• Formulation: PBS with 0.02% Sodium Azide
• Concentration: lot specific
• Purification: Purified by affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: coagulation factor VII
• Database Link:
  NP_062562
  Entrez Gene 2155 Human
  UniProt ID P08709
• Background: Factor VII is a 50kDa multi-domain, single chain plasma glycoprotein synthesised in the liver. It is essential for blood coagulation. Factor VII is converted to the active, two chain, serine protease Factor VIIa via cleavage by thrombin, factor Xa, factor IXa or factor XIIa. Factor VIIa converts factor X to factor Xa, which in turn converts prothrombin to thrombin. This monoclonal antibody inhibits human FVII activity and may also be used to immunodeplete FVII from normal plasma.
• Synonyms: SPCA

Reference Data

• Protein Families: Druggable Genome, Protease
• Protein Pathways: Complement and coagulation cascades