L1CAM Mouse Monoclonal Antibody [Clone ID: UJ127.11]

CAT#: TA353303L

Mouse monoclonal Anti-L1CAM Clone UJ127.11

Specifications

Product Data

• Clone Name: UJ127.11
• Recommended Dilution: ELISA ; IHC ; IP ; WB
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Homogenous suspension of 16 week human foetal brain.
• Formulation: PBS with 0.02% Sodium Azide
• Concentration: lot specific
• Purification: Purified by affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: L1 cell adhesion molecule
• Database Link:
  NP_000416
  Entrez Gene 3897 Human
  UniProt ID P32004
• Background: L1 cell adhesion molecule (L1CAM) is a cell-surface glycoprotein of 220-240kDa (doublet) and member of the neural adhesion molecule family of the immunoglobulin superfamily. L1CAM is implicated in the development of the nervous system and its expression is restricted to tissues arising from the neuroectoderm. L1CAM is present on tumours of neuroectodermal and glial origin (e.g. neuroblastoma and schwannomas). UJ127.11 may be useful in the diagnosis of embryonic tumours (e.g. neuroblastoma) or for the purpose of bone marrow purging. The antigen is present on tumours of neuroectodermal and glial origin.eg neuroblastoma and schwannomas.
• Synonyms: CAML1; CD171; HSAS; HSAS1; MASA; MIC5; N-CAM-L1; N-CAML1; NCAM-L1; S10; SPG1

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
• Protein Pathways: Axon guidance, Cell adhesion molecules (CAMs)