Ki67 (MKI67) Rabbit Polyclonal Antibody

CAT#: TA354200

Rabbit anti Ki-67 Polyclonal Antibody

Product Images

IHC: Human lymph node stained with Anti-Ki-67 antibody at 1:200 for 10 min at RT. Staining of formalin-fixed tissue requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min.

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: WB 0.1-1 µg/ml ELISA 0.01-0.1 µg/ml IP 2-5 µg/ml IHC 2-10 µg/ml FC 5-10 µg/ml
• Reactivities: Human Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A synthetic peptide derived from human Ki-67 protein
• Formulation: This affinity purified antibody is supplied in sterile Phosphate buffered saline (pH7.2) containing antibody stabilizer.
• Purification: The Rabbit IgG is purified by Epitope Affinity Purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 345 & 395 kDa
• Gene Name: marker of proliferation Ki-67
• Database Link:
  NP_001139438
  Entrez Gene 291234 RatEntrez Gene 4288 Human
  UniProt ID P46013
• Background: Ki-67, a proliferation marker is a nuclear protein that is associated with and may be necessary for cellular proliferation. It can be used as a biomarker with Bcl-2 (an apoptosis inhibitor), P53 and Pax 2 for immunohistostaining in carcinomas diagnosis. The differences in the immunocytochemical expression of those markers are correlated to the results with tumor grade and stage for a further accurate diagnosis.
• Synonyms: KIA; MIB-; MIB-1; PPP1R105

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS