Claudin 12 (CLDN12) Rabbit Polyclonal Antibody

CAT#: TA354356

Rabbit anti Claudin 12 Polyclonal Antibody

Product Images

WB: The whole tissue lysates derived from 100%confluenced MCF7 were immunoblotted by Rabbit anti-Claudin 12 antibody at 1:500 (left Lane ). The immunoreactive band is blocked by preincubation of immunizing peptide (right Lane 2)

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB 0.1-1 µg/ml ELISA 0.01-0.1 µg/ml IP 2-5 µg/ml IHC 2-10 µg/ml FC 5-10 µg/ml
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A synthetic peptide from C-terminus of human claudin 12 protein. This sequence is identical to human, rat, mouse and bovine.
• Formulation: This affinity purified antibody is supplied in sterile Phosphate buffered saline (pH7.2) containing antibody stabilizer.
• Purification: The Rabbit IgG is purified by Epitope Affinity Purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 27 kDa
• Gene Name: claudin 12
• Database Link:
  NP_001172001
  Entrez Gene 9069 Human
  UniProt ID P56749
• Background: The claudin superfamily consists of many structurally related proteins in humans. These proteins, which include claudin 1 through 18, are important structural and functional components of tight junctions in paracellular transport. Claudins are located in both epithelial and endothelial cells in all tight junction-bearing tissues. Claudins, which consist of four trans-membrane domains and two extracellular loops, make up tight junction strands. Claudin 12 is 244 aa residues. It is expressed in the inner ear and bladder epithelium, and it is over-expressed in colorectal carcinomas.
• Synonyms: OTTHUMP00000067944

Reference Data

• Protein Families: Transmembrane