BTF (BCLAF1) Rabbit Polyclonal Antibody
CAT#: TA355007
Rabbit Polyclonal Anti-BCLAF1 Antibody
Other products for "BCLAF1"
Specifications
Product Data | |
Applications | IHC, WB |
Recommended Dilution | WB: 0.5-1µg/ml.IHC starting at 5µg/mL. |
Reactivities | Human, Mouse, Rat |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | BCLAF1 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human BCLAF1. The immunogen is located within amino acids 820 - 870 of BCLAF1. |
Formulation | BCLAF1 antibody is supplied in PBS containing 0.02% sodium azide. |
Concentration | 1 mg/ml |
Purification | BCLAF1 antibody is affinity chromatography purified via peptide column. |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | Predicted: 101 kDa; Observed: 105 kDa |
Gene Name | BCL2 associated transcription factor 1 |
Database Link | |
Background | The BCL2-associated transcription factor 1 (BCLAF1) is a transcriptional repressor that interacts with several members of the BCL2 family of proteins. Overexpression of this protein induces apoptosis, which can be suppressed by co-expression of BCL2 proteins (1). BCLAF1 localizes to dot-like structures throughout the nucleus, and redistributes to a zone near the nuclear envelope in cells undergoing apoptosis. (2). More recent studies have suggested BCLAF1 plays roles in processes not associated with actions of the BCL2 family members, including lung development, T cell activation, and post-transcriptional processes that affect mRNA metabolism (3). |
Synonyms | bK211L9.1; BTF; KIAA0164 |
Note | BCLAF1 antibody can be used for detection of BCLAF1 by Western blot at 0.5 - 1 µg/ml. Antibody can also be used for immunohistochemistry starting at 5 µg/mL. |
Reference Data | |
Protein Families | Transcription Factors |
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