SUSD3 Rabbit Polyclonal Antibody
CAT#: TA355016
Rabbit Polyclonal Anti-SUSD3 Antibody
Other products for "SUSD3"
Specifications
Product Data | |
Applications | IF, WB |
Recommended Dilution | WB: 1-2µg/mL.IHC starting at 5µg/mL. |
Reactivities | Human, Mouse |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | SUSD3 antibody was raised against a 16 amino acid peptide from near the center of human SUSD3. The immunogen is located within amino acids 120 - 170 of SUSD3. |
Formulation | SUSD3 Antibody is supplied in PBS containing 0.02% sodium azide. |
Concentration | 1 mg/ml |
Purification | SUSD3 Antibody is affinity chromatography purified via peptide column. |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | Predicted: 16, 22, 23, 28 kDa; Observed: 23 kDa |
Gene Name | sushi domain containing 3 |
Database Link | |
Background | Little is known of the function of the sushi domain containing 3 protein (SUSD3), but its expression has been reported in estrogen receptor-alpha (ERalpha)-positive breast tumors with decreased expression reported in aggressive malignant tumors (1,2). Recently, SUSD3 has been found to promote estrogen-dependent cell proliferation and may regulate cell-cell and cell-substrate interactions and migration in breast cancer (3). Furthermore, elevated SUSD3 mRNA levels were observed in aromatase inhibitor-responsive breast tumors, suggesting that it may also serve as a novel predictor of response to endocrine therapy and a potential therapeutic target (3). |
Synonyms | MGC26847 |
Note | SUSD3 antibody can be used for the detection of SUSD3 by Western blot at 1 - 2 µg/mL. Antibody can also be used for immunocytochemistry starting at 5 µg/mL. |
Reference Data | |
Protein Families | Transmembrane |
Documents
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