CD22 Rabbit Monoclonal Antibody [Clone ID: DM12]

CAT#: TA355166

CD22 rabbit monoclonal antibody, clone DM12

Product Images

Figure 1. Flow cytometry data of serially titrated Rabbit anti-CD22 monoclonal antibody (clone: DM12) on Raji cells. The Y-axis represents the mean fluorescence intensity (MFI) while the X-axis represents the concentration of IgG used.

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  Figure 2. Affinity ranking of different Rabbit anti-CD22 mAb clones by titration of different concentration onto Raji cells. The Y-axis represents the mean fluorescence intensity (MFI) while the X-axis represents the concentration of IgG used.

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  Figure 3. Phylogenetic analysis of amino acid sequence of different Rabbit Anti-CD22 mAb clones. A) Heavy chain and B) Light chain.

Specifications

Product Data

• Clone Name: DM12
• Applications: ELISA, FC, IF, WB
• Recommended Dilution: Flow Cyt 1/100
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Monoclonal
• Immunogen: Recombinant human CD22 (Asp20-Arg687) (TP723928)produced by using human HEK293 cells
• Formulation: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
  Preservative: 0.1% Procline 300
• Reconstitution Method: Reconstitute with deionized water
• Purification: Purified from cell culture supernatant by affinity chromatography
• Conjugation: Unconjugated
• Storage: Store at -20°C for 12 months (Avoid repeated freezing and thawing)
• Stability: 12 months from date of despatch
• Predicted Protein Size: 95kDa
• Gene Name: CD22 molecule
• Database Link:
  Entrez Gene 933 Human
  UniProt ID P20273
• Background: CD22 (CD22 Molecule) is a Protein Coding gene. Diseases associated with CD22 include Refractory Hematologic Cancer and Hairy Cell Leukemia. Among its related pathways are Downstream signaling events of B Cell Receptor (BCR) and Hematopoietic cell lineage. Gene Ontology (GO) annotations related to this gene include carbohydrate binding. An important paralog of this gene is SIGLEC1.
• Synonyms: BL-CAM; FLJ22814; Leu-14; MGC130020; Siglec-2; SIGLEC2