Her2 (ERBB2) Mouse Monoclonal Antibody [Clone ID: 10A7]

CAT#: TA355267

C-ERBB-2 Mouse Monoclonal Antibody

Specifications

Product Data

• Clone Name: 10A7
• Applications: IHC
• Recommended Dilution: 1:80
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Prokaryotic recombinant protein corresponding to a portion of the external domain of the human c-erbB-2 oncoprotein molecule
• Specificity: Human c-erbB-2 oncoprotein (external domain)
• Formulation: Liquid tissue culture supernatant containing sodium azide as a preservative
• Conjugation: Unconjugated
• Storage: Store at 2-8°C
• Stability: 12 months
• Gene Name: erb-b2 receptor tyrosine kinase 2
• Database Link:
  Entrez Gene 2064 Human
• Background: The c-erbB-2 oncoprotein is closely related in structure to the epidermal growth factor receptor and is a member of a large family of cell surface growth factor receptors. c-erbB-2 oncoprotein is reported to be detectable in a proportion of breast and other adenocarcinomas as well as transitional cell carcinomas. c-erbB-2 oncoprotein is present in a wide variety of cell types in a range of normal human fetal and adult tissues, including breast, stomach and ovary. CB11 detects the internal domain of the c-erbB-2 oncoprotein. CBE-356 detects the external domain of the c-erbB-2 oncoprotein.
• Synonyms: C-erbB-2; CD340; erbB-2; HER-2; HER-2/neu; HER2; herstatin; NEU; NGL; p185erbB2; TKR1