MelanA (MLANA) Mouse Monoclonal Antibody [Clone ID: A103]
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Specifications
Product Data | |
Clone Name | A103 |
Applications | IHC |
Recommended Dilution | 1:50 |
Reactivities | Human |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Prokaryotic recombinant fusion protein corresponding to the human melan A molecule |
Specificity | Human melan A, recognizing a 20 to 22 kD doublet in melan A mRNA-positive melanoma cell lines. Does not react with melan A mRNA_x0002_negative cell lines. |
Formulation | Liquid tissue culture supernatant containing sodium azide as a preservative |
Conjugation | Unconjugated |
Storage | Store at 2-8°C |
Stability | 12 months |
Gene Name | melan-A |
Database Link | |
Background | Melan A, a product of the MART-1 gene, is a melanocyte differentiation marker recognized by autologous cytotoxic T lymphocytes. Other melanoma-associated markers recognized by autologous cytotoxic T cells are reported to include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1 and GAGE-1. The analysis of these different molecules and their expression in individual melanomas may be of help in the study of their particular molecular roles in melanocyte differentiation and tumorigenesis. |
Synonyms | MART-1; MART1; melan-A; OTTHUMP00000021037; OTTHUMP00000021038 |
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