MelanA (MLANA) Mouse Monoclonal Antibody [Clone ID: A103]

CAT#: TA355311

Melan A Mouse Monoclonal Antibody

Specifications

Product Data

• Clone Name: A103
• Applications: IHC
• Recommended Dilution: 1:50
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Prokaryotic recombinant fusion protein corresponding to the human melan A molecule
• Specificity: Human melan A, recognizing a 20 to 22 kD doublet in melan A mRNA-positive melanoma cell lines. Does not react with melan A mRNA_x0002_negative cell lines.
• Formulation: Liquid tissue culture supernatant containing sodium azide as a preservative
• Conjugation: Unconjugated
• Storage: Store at 2-8°C
• Stability: 12 months
• Gene Name: melan-A
• Database Link:
  Entrez Gene 2315 Human
• Background: Melan A, a product of the MART-1 gene, is a melanocyte differentiation marker recognized by autologous cytotoxic T lymphocytes. Other melanoma-associated markers recognized by autologous cytotoxic T cells are reported to include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1 and GAGE-1. The analysis of these different molecules and their expression in individual melanomas may be of help in the study of their particular molecular roles in melanocyte differentiation and tumorigenesis.
• Synonyms: MART-1; MART1; melan-A; OTTHUMP00000021037; OTTHUMP00000021038