SFTPA1 Mouse Monoclonal Antibody [Clone ID: 32000000000000]

CAT#: TA355347

Surfactant Protein A Mouse Monoclonal Antibody

Specifications

Product Data

• Clone Name: 32000000000000
• Applications: IHC
• Recommended Dilution: 1:2000
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Prokaryotic recombinant protein corresponding to the 104–246 amino acid region of the human prosurfactant A molecule
• Specificity: Human surfactant protein A (prosurfactant A)
• Formulation: Liquid tissue culture supernatant containing sodium azide as a preservative
• Conjugation: Unconjugated
• Storage: Store at 2-8°C
• Stability: 12 months
• Gene Name: surfactant protein A1
• Database Link:
  Entrez Gene 653509 Human
• Background: Pulmonary surfactant plays a critical role in maintaining the structural integrity of the respiratory epithelium by reducing surface tension during expiration. It is a lipoprotein complex which is synthesized and secreted into the alveoli of the lung by type II pneumocytes. Lung surfactant protein-A (SP-A) is a major phospholipid-associated glycoprotein in surfactant and is a member of the C-type lectin superfamily that also inhibits lipid secretion and enhances the uptake of phospholipid by alveolar type II cells. Levels of SP-A in amniotic fluid are reported to reflect the degree of fetal lung maturity and inadequate levels of surfactant at birth, a frequent occurrence in premature infants, results in respiratory failure.
• Synonyms: COLEC4; FLJ50593; FLJ51913; FLJ61144; FLJ77898; FLJ79095; FLJ99559; MGC133365; PSAP; PSP-A; PSPA; SFTP1; SFTPA; SP-A; SP-A1