Tartrate Resistant Acid Phosphatase (ACP5) Mouse Monoclonal Antibody [Clone ID: 2600000]

CAT#: TA355349

Tartrate-Resistant Acid Phosphatase (TRAP) Mouse Monoclonal Antibody

Specifications

Product Data

• Clone Name: 2600000
• Applications: IHC
• Recommended Dilution: 1:300
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2b
• Clonality: Monoclonal
• Immunogen: Prokaryotic recombinant fusion protein corresponding to the N-terminal portion of the TRAP molecule
• Specificity: Human tartrate-resistant acid phosphatase (TRAP)
• Formulation: Liquid tissue culture supernatant containing sodium azide as a preservative
• Conjugation: Unconjugated
• Storage: Store at 2-8°C
• Stability: 12 months
• Gene Name: acid phosphatase 5, tartrate resistant
• Database Link:
  Entrez Gene 54 Human
• Background: Tartrate-resistant acid phosphatase (TRAP) is a basic, iron-binding protein with high activity towards phosphoproteins, ATP and 4-nitrophenyl phosphate. This isoenzyme has been reported through different applications to be expressed in human alveolar macrophages, osteoclasts, spleen and liver. Expression of TRAP is reported to be increased in the spleen and monocytes of individuals with Gaucher's disease, Hodgkin's disease and the sera of individuals undergoing active bone turnover. Elevated levels are also reported to be associated with various B cell and T cell leukemias and lymphomas, decidual cells, syncytiotrophoblasts and some macrophages distributed throughout maternal and embryonic tissues.
• Synonyms: MGC117378; TR-AP; TRAP; TrATPase