Fadd Rabbit Polyclonal Antibody

CAT#: TA355442

FADD Antibody - C-terminal region

Product Images

WB Suggested Anti-FADD Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:62500 Positive Control: SP2/0 cell lysate

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  Host: Mouse Target Name: FADD Sample Tissue: Mouse Heart Antibody Dilution: 1ug/ml

Specifications

Product Data

• Applications: WB
• Reactivities: Mouse
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of mouse FADD
• Specificity: Expected reactivity: Mouse
  Homology: Mouse: 100%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 23kDa
• Gene Name: Fas (TNFRSF6)-associated via death domain
• Database Link:
  NP_034305
  Entrez Gene 14082 Mouse
  UniProt ID Q61160
• Background: Fadd is apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis.
• Synonyms: GIG3; MGC8528; MORT1