Arnt Rabbit Polyclonal Antibody

CAT#: TA355466

Arnt Antibody - C-terminal region

Product Images

WB Suggested Anti-Arnt Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: Rat Liver

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  Researcher: Hiten D. Mistry, King's College London Application: IHC Species + Tissue/Cell type: Human placenta Primary antibody dilution: 1:200 Secondary antibody: Anti-rabbit-HRP Secondary antibody dilution: 1:5000

Specifications

Product Data

• Applications: IHC, WB
• Reactivities: Human, Rat
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide corresponding to a region of Rat
• Specificity: Expected reactivity: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Sheep
  Homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 92%; Rabbit: 92%; Rat: 100%; Sheep: 100%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 88kDa
• Gene Name: aryl hydrocarbon receptor nuclear translocator
• Database Link:
  NP_036912
  Entrez Gene 405 HumanEntrez Gene 25242 Rat
  UniProt ID P41739
• Background: Arnt is required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAH procarcinogens. The heterodimer with HIF1A or EPAS1/HIF2A functions as a transcriptional regulator of the adaptive response to hypoxia.
• Synonyms: bHLHe2; HIF-1beta; HIF1B; HIF1BETA; TANGO