SCN7A Rabbit Polyclonal Antibody

CAT#: TA355736

SCN7A Antibody - N-terminal region

Product Images

Host: Rabbit Target Name: SCN7A Sample Type: Fetal Thymus lysates Antibody Dilution: 1.0ug/ml

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of human SCN7A
• Specificity: Expected reactivity: Dog, Guinea Pig, Human, Mouse, Rat
  Homology: Dog: 79%; Guinea Pig: 80%; Human: 100%; Mouse: 79%; Rat: 79%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 83kDa
• Gene Name: sodium voltage-gated channel alpha subunit 7
• Database Link:
  NP_002967.2
  Entrez Gene 6332 Human
  UniProt ID Q01118
• Background: This gene encodes one of the many voltage-gated sodium channel proteins. For proper functioning of neurons and muscles during action potentials, voltage-gated sodium channels direct sodium ion diffusion for membrane depolarization. This sodium channel protein has some atypical characteristics; the similarity between the human and mouse proteins is lower compared to other orthologous sodium channel pairs. Also, the S4 segments, which sense voltage changes, have fewer positive charged residues that in other sodium channels; domain 4 has fewer arginine and lysine residues compared to other sodium channel proteins. Several alternatively spliced transcript variants exist, but the full-length natures of all of them remain unknown.
• Synonyms: OTTHUMP00000205008; SCN6A