Nme1 Rabbit Polyclonal Antibody

CAT#: TA355975

Nme1 Antibody - C-terminal region

Product Images

DB Suggested Anti-Nme1 antibody Titration: 0.5 ug/ml Positive Control: Recomninant human NME2 protein

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  WB Suggested Anti-Nme1 Antibody Titration: 1.0 ug/ml Positive Control: Mouse Liver

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  Lanes: 1. 20 ug human MDA-MB-231 cell lysate 2. 20 ug murine 4T1 primary breast tumor cell lysate 3. 20 ug human MDA-MB-231 cell lysate 4. 20 ug murine 4T1 primary breast tumor cell lysate Primary Antibody Dilution: 1:2000 Secondary Antibody: Goat anti-rabbit-Alexa Fluor 680 Secondary Antibody Dilution: 1:25,000 Gene Name: Nme1 Submitted by: Anonymous

Specifications

Product Data

• Applications: WB
• Reactivities: Human, Mouse
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: Expected reactivity: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat, Yeast
  Homology: Cow: 100%; Dog: 100%; Guinea Pig: 92%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Yeast: 92%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 17kDa
• Gene Name: NME/NM23 nucleoside diphosphate kinase 1
• Database Link:
  NP_032730
  Entrez Gene 4830 HumanEntrez Gene 18102 Mouse
  UniProt ID P15532
• Background: Nme1 has a major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. It possesses nucleoside-diphosphate kinase, serine/threonine-specific protein kinase, geranyl and farnesyl pyrophosphate kinase, histidine protein kinase and 3'-5' exonuclease activities. It is involved in cell proliferation, differentiation and development, signal transduction, G protein-coupled receptor endocytosis, and gene expression. Itis required for neural development including neural patterning and cell fate determination.
• Synonyms: AWD; GAAD; NB; NBS; NDPK-A; NDPKA; NM23; NM23-H1; OTTHUMP00000174772