Fmr1 Rabbit Polyclonal Antibody

CAT#: TA356089

Fmr1 Antibody - C-terminal region

Product Images

WB Suggested Anti-Fmr1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: Rat Lung

Specifications

Product Data

• Applications: WB
• Reactivities: Rat
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide corresponding to a region of Rat
• Specificity: Expected reactivity: Cow, Dog, Guinea Pig, Human, Mouse, Rabbit, Rat
  Homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 67kDa
• Gene Name: fragile X mental retardation 1
• Database Link:
  NP_434691
  Entrez Gene 24948 Rat
  UniProt ID Q80WE1
• Background: Fmr1 is a translation repressor. Fmr1 is a component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates translation repression. RNA-binding protein that plays a role in intracellular RNA transport and in the regulation of translation of target mRNAs.Fmr1 is associated with polysomes. Fmr1 is involved in the transport of mRNA from the nucleus to the cytoplasm. Fmr1 binds strongly to poly(G), binds moderately to poly(U) but shows very little binding to poly(A) or poly(C).
• Synonyms: FMRP; FRAXA; MGC87458; POF; POF1