STUB1 Rabbit Polyclonal Antibody

CAT#: TA356315

STUB1 Antibody - N-terminal region

Product Images

WB Suggested Anti-STUB1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: Human Spleen

• 

  Lanes: 1:1ug insoluble STUB1 protein, 2:1ug soluble STUB1 protein, 3:1ug EPM2A protein, 4:1ug insoluble PPP1R3°C protein, 5:1ug soluble PPP1R3°C protein Primary Antibody Dilution: 1:2500 Secondary Antibody: Anti-rabbit-AP Secondary Antibody Dilution: 1:20,000 Gene Name: STUB1 Submitted by: Pedro Castanheira, Biocant

• 

Specifications

Product Data

• Applications: IHC, WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human STUB1
• Specificity: Expected reactivity: Cow, Guinea Pig, Human, Mouse, Rat, Zebrafish
  Homology: Cow: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 93%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 35kDa
• Gene Name: STIP1 homology and U-box containing protein 1
• Database Link:
  NP_005852
  Entrez Gene 10273 Human
  UniProt ID Q9UNE7
• Background: STUB1 modulates the activity of several chaperone complexes, including Hsp70, Hsc70 and Hsp90. It has E3 ubiquitin-protein ligase activity and targets misfolded chaperone substrates towards proteasomal degradation. STUB1 mediates transfer of non-canonical short ubiquitin chains to HSPA8 that have no effect on HSPA8 degradation.
• Synonyms: CHIP; HSPABP2; NY-CO-7; SDCCAG7; UBOX1

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Ubiquitin mediated proteolysis