nSMase (SMPD2) Rabbit Polyclonal Antibody

CAT#: TA356527

SMPD2 Antibody - N-terminal region

Product Images

WB Suggested Anti-SMPD2 Antibody Titration: 1.25ug/ml Positive Control: HepG2 cell lysate

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SMPD2
• Specificity: Expected reactivity: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
  Homology: Cow: 79%; Dog: 86%; Guinea Pig: 79%; Horse: 86%; Human: 100%; Mouse: 77%; Rabbit: 79%; Rat: 79%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Protein A purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 48kDa
• Gene Name: sphingomyelin phosphodiesterase 2
• Database Link:
  NP_003071
  Entrez Gene 6610 Human
  UniProt ID O60906
• Background: SMPD2 converts sphingomyelin to ceramide. Hydrolyze 1-acyl-2-lyso-sn-glycero-3-phosphocholine (lyso-PC) and 1-O-alkyl-2-lyso-sn-glycero-3-phosphocholine (lyso-platelet-activating factor). The physiological substrate seems to be Lyso-PAF.
• Synonyms: ISC1; Lyso-PAF-PLC; N-SMase; nSMase; NSMASE1

Reference Data

• Protein Families: Transmembrane
• Protein Pathways: Metabolic pathways, Sphingolipid metabolism