PCDHB5 Rabbit Polyclonal Antibody

CAT#: TA356630

PCDHB5 Antibody - N-terminal region

Product Images

Host: Rabbit Target Name: PCDHB5 Sample Type: 293T Whole Cell lysates Antibody Dilution: 1.0ug/ml

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human PCDHB5
• Specificity: Expected reactivity: Cow, Guinea Pig, Human, Mouse, Rabbit, Rat
  Homology: Cow: 77%; Guinea Pig: 85%; Human: 100%; Mouse: 92%; Rabbit: 75%; Rat: 100%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 87kDa
• Gene Name: protocadherin beta 5
• Database Link:
  NP_056484
  Entrez Gene 26167 Human
  UniProt ID Q9Y5E4
• Background: This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.
• Synonyms: DKFZp586B0217; PCDH-beta-5; PCDH-BETA5