Morf4l1 Rabbit Polyclonal Antibody

CAT#: TA356667

Morf4l1 Antibody - middle region

Product Images

WB Suggested Anti-Morf4l1 Antibody Titration: 1.0 ug/ml Positive Control: Mouse Small Intestine

Specifications

Product Data

• Applications: WB
• Reactivities: Mouse
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: Expected reactivity: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat, Zebrafish
  Homology: Cow: 93%; Dog: 93%; Guinea Pig: 86%; Horse: 93%; Human: 93%; Mouse: 93%; Pig: 93%; Rabbit: 93%; Rat: 93%; Zebrafish: 85%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 41kDa
• Gene Name: mortality factor 4 like 1
• Database Link:
  NP_001034236
  Entrez Gene 21761 Mouse
  UniProt ID P60762
• Background: Morf4l1 is a component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage.
• Synonyms: Eaf3; FWP006; HsT17725; MEAF3; MGC10631; MORFRG15; MRG15; S863-6