SERPINB6 Rabbit Polyclonal Antibody

CAT#: TA357570

SERPINB6 Antibody - middle region

Product Images

WB Suggested Anti-SERPINB6 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: Human Placenta

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SERPINB6
• Specificity: Expected reactivity: Cow, Human
  Homology: Cow: 79%; Human: 100%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 41kDa
• Gene Name: serpin family B member 6
• Database Link:
  NP_004559
  Entrez Gene 5269 Human
  UniProt ID P35237
• Background: The protein encoded by this gene is a member of the serpin (serine proteinase inhibitor) superfamily, and ovalbumin(ov)-serpin subfamily. It was originally discovered as a placental thrombin inhibitor. The mouse homolog was found to be expressed in the hair cells of the inner ear. Mutations in this gene are associated with nonsyndromic progressive hearing loss, suggesting that this serpin plays an important role in the inner ear in the protection against leakage of lysosomal content during stress, and that loss of this protection results in cell death and sensorineural hearing loss. Alternatively spliced transcript variants have been found for this gene.
• Synonyms: CAP; DKFZp686I04222; MGC111370; MSTP057; OTTHUMP00000017778; OTTHUMP00000017779; OTTHUMP00000017781; OTTHUMP00000017782; PI-6; PI6; PTI; SPI3

Reference Data

• Protein Families: Druggable Genome