Calpain 3 (CAPN3) Rabbit Polyclonal Antibody

CAT#: TA357770

CAPN3 Antibody - C-terminal region

Product Images

WB Suggested Anti-CAPN3 Antibody Titration: 1.0 ug/ml Positive Control: OVCAR-3 Whole Cell

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: Expected reactivity: Cow, Dog, Guinea Pig, Horse, Human, Rabbit, Rat, Sheep
  Homology: Cow: 79%; Dog: 92%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Rabbit: 86%; Rat: 85%; Sheep: 86%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 93kDa
• Gene Name: calpain 3
• Database Link:
  NP_077320
  Entrez Gene 825 Human
  UniProt ID P20807-3
• Background: Calpain, a heterodimer consisting of a large and a small subunit, is a major intracellular protease, although its function has not been well established. This gene encodes a muscle-specific member of the calpain large subunit family that specifically binds to titin. Mutations in this gene are associated with limb-girdle muscular dystrophies type 2A. Alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms and some variants are ubiquitously expressed.
• Synonyms: CANP3; CANPL3; LGMD2; LGMD2A; MGC4403; MGC10767; MGC11121; MGC14344; nCL-1; NCL1; OTTHUMP00000161194; OTTHUMP00000161196; p94

Reference Data

• Protein Families: Druggable Genome, Protease