H2AC8 Rabbit Polyclonal Antibody

CAT#: TA357783

HIST1H2AE Antibody - middle region

Product Images

WB Suggested Anti-HIST1H2AE Antibody Titration: 1.0 ug/ml Positive Control: RPMI-8226 Whole Cell

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: Expected reactivity: Cow, Human, Pig, Rat
  Homology: Cow: 100%; Human: 100%; Pig: 100%; Rat: 100%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 14kDa
• Gene Name: histone cluster 1, H2ae
• Database Link:
  NP_066390
  Entrez Gene 3012 Human
  UniProt ID Q7L7L0
• Background: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H2A family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.
• Synonyms: H2A.1; H2A.2; H2A/a; H2A/m; H2AFA; H2AFM

Reference Data

• Protein Pathways: Systemic lupus erythematosus