POLG2 Rabbit Polyclonal Antibody

CAT#: TA358012

POLG2 Antibody - N-terminal region

Product Images

WB Suggested Anti-POLG2 Antibody Titration: 1.0 ug/ml Positive Control: Fetal kidney

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: Expected reactivity: Human
  Homology: Human: 100%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 53kDa
• Gene Name: polymerase (DNA) gamma 2, accessory subunit
• Database Link:
  NP_009146
  Entrez Gene 11232 Human
  UniProt ID Q9UHN1
• Background: This gene encodes the processivity subunit of the mitochondrial DNA polymerase gamma. The encoded protein forms a heterotrimer containing one catalytic subunit and two processivity subunits. This protein enhances DNA binding and promotes processive DNA synthesis. Mutations in this gene result in autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions.
• Synonyms: HP55; MTPOLB; p55; PEOA4; POLB; PolG-beta; POLGB

Reference Data

• Protein Families: Stem cell - Pluripotency
• Protein Pathways: Metabolic pathways