Vasopressin V1b receptor (AVPR1B) Rabbit Polyclonal Antibody

CAT#: TA358319

AVPR1B Antibody - C-terminal region

Product Images

WB Suggested Anti-AVPR1B Antibody Titration: 1.0 ug/ml Positive Control: RPMI-8226 Whole Cell

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: Expected reactivity: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Sheep
  Homology: Cow: 93%; Dog: 100%; Guinea Pig: 93%; Horse: 75%; Human: 100%; Mouse: 86%; Rabbit: 86%; Rat: 86%; Sheep: 93%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 47kDa
• Gene Name: arginine vasopressin receptor 1B
• Database Link:
  NP_000698
  Entrez Gene 553 Human
  UniProt ID P47901
• Background: The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1A, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor is primarily located in the anterior pituitary, where it stimulates ACTH release. It is expressed at high levels in ACTH-secreting pituitary adenomas as well as in bronchial carcinoids responsible for the ectopic ACTH syndrome. A spliced antisense transcript of this gene has been reported but its function is not known.
• Synonyms: AVPR3; V1bR; VPR3

Reference Data

• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Vascular smooth muscle contraction